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Genetic Linkage

Human Stem Cells from Amniotic Fluid

Stem cells from amniotic fluid are like Russian nesting dolls -- they are derived from the cells that would become sperm or eggs in a fetus.
A new source of human stem cells reminds me of Russian nesting dolls: They come from amniotic fluid. When exposed to a seizure drug (valproic acid), they divide to give rise to cells that can specialize as nearly any cell type – they are “pluripotent,” like embryonic stem (ES) cells. But the new stem cells are most like precursor cells in a fetus that become sperm and eggs. And so the cells derived from an organ in a pregnant woman might otherwise, if paired with the opposite type of sex cell, have become her grandchildren! Read More 
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Stem Cell Ups and Downs

We expect too much of stem cells. The February 3 issue of Nature reveals both a setback and a stupendous achievement in the field.

An article in the news section takes induced pluripotent stem cells (iPS cells) down  Read More 
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