New edition just published! Order from publisher or Amazon


Tags

Glenn Nichols, surrounded by his hospice team. The author is in yellow.

Genetic Linkage

Craig Venter’s Synthetic Genome 3.0 Evokes Classic Experiments

March 31, 2016

Tags: synthetic biology, synthetic genome, J. Craig Venter

Is a synthetic genome new life?
J. Craig Venter and his colleagues at Synthetic Genomics Inc update their efforts to create a “hypothetical minimal genome" in Science.

“JCVI-syn3.0,” or syn3.0 for short, is about 531,000 DNA base pairs organized into 473 genes, serially transplanted into cells of the tiny and fast-replicating Mycoplasma mycoides and M. capricolum. The first iteration of the smallest synthetic genome, JVCI-syn1.0, has just over a million base pairs, and the intermediate JCVI-syn2.0 has 576,000.

While syn3.0 will serve as a foundation for future synthetic biology, it reminds me of two favorite experiments from more than half a century ago. (more…)

instruction
Project to engage students in helping families with rare genetic diseases
Book Club Reader's Guide
Many challenging questions to stimulate thought and discussion.
Instructor's Guide
38 discussion questions to get students thinking and talking about gene therapy, including the science, ethical issues, and the drug approval process.
Narrative science
The Forever Fix is the uplifting true story of 8-year-old Corey Haas, who was cured of hereditary blindness just 4 days after gene therapy.
College Textbooks
A spectacularly-illustrated, clearly written human anatomy and physiology textbook, used in pre-health profession programs throughout the U.S.
A highly engaging, clearly written, beautifully illustrated introduction to the science of human genetics for the non-scientist. Now in its 10th edition.
Nonfiction
An ideal starting point for anyone who wants to know more about genes, DNA, genomes, and the genetic ties that bind us all.

Quick Links