New edition just published! Order from publisher or Amazon


Tags

Glenn Nichols, surrounded by his hospice team. The author is in yellow.

Genetic Linkage

Human Stem Cells from Amniotic Fluid

July 4, 2012

Tags: human embryonic stem cells, induced pluripotent stem cells, transcriptome, amniotic stem cells, valproic acid

Stem cells from amniotic fluid are like Russian nesting dolls -- they are derived from the cells that would become sperm or eggs in a fetus.
A new source of human stem cells reminds me of Russian nesting dolls: They come from amniotic fluid. When exposed to a seizure drug (valproic acid), they divide to give rise to cells that can specialize as nearly any cell type – they are “pluripotent,” like embryonic stem (ES) cells. But the new stem cells are most like precursor cells in a fetus that become sperm and eggs. And so the cells derived from an organ in a pregnant woman might otherwise, if paired with the opposite type of sex cell, have become her grandchildren! (more…)

Stem Cell Ups and Downs

February 12, 2011

Tags: stem cells, human embryonic stem cells, induced pluripotent stem cells, iPS cells, reprogrammed cells, embryo, fetus, intestine, Crohn's disease, irritable bowel syndrome

We expect too much of stem cells. The February 3 issue of Nature reveals both a setback and a stupendous achievement in the field.

An article in the news section takes induced pluripotent stem cells (iPS cells) down (more…)

instruction
Project to engage students in helping families with rare genetic diseases
Book Club Reader's Guide
Many challenging questions to stimulate thought and discussion.
Instructor's Guide
38 discussion questions to get students thinking and talking about gene therapy, including the science, ethical issues, and the drug approval process.
Narrative science
The Forever Fix is the uplifting true story of 8-year-old Corey Haas, who was cured of hereditary blindness just 4 days after gene therapy.
College Textbooks
A spectacularly-illustrated, clearly written human anatomy and physiology textbook, used in pre-health profession programs throughout the U.S.
A highly engaging, clearly written, beautifully illustrated introduction to the science of human genetics for the non-scientist. Now in its 11th edition, 12th to be published in September 2018.
Nonfiction
An ideal starting point for anyone who wants to know more about genes, DNA, genomes, and the genetic ties that bind us all.

Quick Links