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Glenn Nichols, surrounded by his hospice team. The author is in yellow.

Genetic Linkage

My Husbandís Rare Cancer

June 7, 2016

Tags: appendix cancer

ďGenotyping isnít standard of care, so we donít do it,Ē said the surgeon dismissively to me a week ago, as if Iíd asked him to bleed my husband or feel his head bumps.

Since the surgeon had just removed a foot of Larryís colon, I stifled the urge to shout Gleevec! Avastin! Herceptin! Iíd asked about testing the cancer cells for variants of well-studied oncogenes and tumor suppressor genes. The mutational state of tumor cells at the time of removal, especially given the rarity of the cancerís origin Ė the appendix -- might prove informative should further treatment become necessary, even if thatís not for many years. (more…)

instruction
Project to engage students in helping families with rare genetic diseases
Book Club Reader's Guide
Many challenging questions to stimulate thought and discussion.
Instructor's Guide
38 discussion questions to get students thinking and talking about gene therapy, including the science, ethical issues, and the drug approval process.
Narrative science
The Forever Fix is the uplifting true story of 8-year-old Corey Haas, who was cured of hereditary blindness just 4 days after gene therapy.
College Textbooks
A spectacularly-illustrated, clearly written human anatomy and physiology textbook, used in pre-health profession programs throughout the U.S.
A highly engaging, clearly written, beautifully illustrated introduction to the science of human genetics for the non-scientist. Now in its 11th edition, 12th to be published in September 2018.
Nonfiction
An ideal starting point for anyone who wants to know more about genes, DNA, genomes, and the genetic ties that bind us all.

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